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Patterns of Human Local Cerebral Glucose Metabolism During Epileptic Seizures

1982·268 Zitationen·Science
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268

Zitationen

3

Autoren

1982

Jahr

Abstract

Ictal patterns of local cerebral metabolic rate have been studied in epileptic patients by positron computed tomography with 18F-labeled 2-fluoro-2-deoxy-D-glucose. Partial seizures were associated with activation of anatomic structures unique to each patient studied. Ictal increases and decreases in local cerebral metabolism were observed. Scans performed during generalized convulsions induced by electroshock demonstrated a diffuse ictal increase and postictal decrease in cerebral metabolism. Petit mal absences were associated with a diffuse increase in cerebral metabolic rate. The ictal fluorodeoxyglucose patterns obtained from patients do not resemble autoradiographic patterns obtained from common experimental animal models of epilepsy.

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Themen

Advanced MRI Techniques and ApplicationsEpilepsy research and treatmentMedical Imaging Techniques and Applications
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