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Improved Survival with Ipilimumab in Patients with Metastatic Melanoma
15.006
Zitationen
29
Autoren
2010
Jahr
Abstract
Ipilimumab, with or without a gp100 peptide vaccine, as compared with gp100 alone, improved overall survival in patients with previously treated metastatic melanoma. Adverse events can be severe, long-lasting, or both, but most are reversible with appropriate treatment. (Funded by Medarex and Bristol-Myers Squibb; ClinicalTrials.gov number, NCT00094653.)
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Autoren
- F. Stephen Hodi
- Steven O’Day
- David F. McDermott
- Robert Weber
- Jeffrey A. Sosman
- John B.A.G. Haanen
- René González
- Caroline Robert
- Dirk Schadendorf
- Jessica C. Hassel
- Wallace Akerley
- Alfons J.M. van den Eertwegh
- Jose Lutzky
- Paul Lorigan
- Julia Vaübel
- Gerald P. Linette
- David Hogg
- Christian H. Ottensmeier
- Célèste Lebbé
- Christian Peschel
- Ian Quirt
- Joseph I. Clark
- Jedd D. Wolchok
- Jeffrey S. Weber
- Jason Tian
- Michael Yellin
- Geoffrey Nichol
- Axel Hoos
- Walter J. Urba
Institutionen
- Harvard University(US)
- Dana-Farber Cancer Institute(US)
- Angeles Clinic and Research Institute(US)
- Hadassah Medical Center(IL)
- Vanderbilt University Medical Center(US)
- The Netherlands Cancer Institute(NL)
- University of Colorado Denver(US)
- University of Colorado Cancer Center(US)
- Institut Gustave Roussy(FR)
- Essen University Hospital(DE)
- German Cancer Research Center(DE)
- University of Mannheim(DE)
- Heidelberg University(DE)
- Huntsman Cancer Institute(US)
- Amsterdam UMC Location VUmc(NL)
- University Hospital and Clinics(US)
- University Medical Center(US)
- Sylvester Comprehensive Cancer Center(US)
- The Christie Hospital(GB)
- Washington University in St. Louis(US)
- Princess Margaret Hospital(NZ)
- Hampton University(US)
- Saint Louis University Hospital(US)
- Loyola University Medical Center(US)
- Memorial Sloan Kettering Cancer Center(US)
- Moffitt Cancer Center(US)
- Bristol-Myers Squibb (United States)(US)
- Providence Portland Medical Center(US)