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Simultaneous MR/PET Imaging of the Human Brain: Feasibility Study
470
Zitationen
12
Autoren
2008
Jahr
Abstract
The purpose of this study was to apply a magnetic resonance (MR) imaging-compatible positron emission tomographic (PET) detector technology for simultaneous MR/PET imaging of the human brain and skull base. The PET detector ring consists of lutetium oxyorthosilicate (LSO) scintillation crystals in combination with avalanche photodiodes (APDs) mounted in a clinical 3-T MR imager with use of the birdcage transmit/receive head coil. Following phantom studies, two patients were simultaneously examined by using fluorine 18 fluorodeoxyglucose (FDG) PET and MR imaging and spectroscopy. MR/PET data enabled accurate coregistration of morphologic and multifunctional information. Simultaneous MR/PET imaging is feasible in humans, opening up new possibilities for the emerging field of molecular imaging.
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Autoren
Institutionen
- University of Tübingen(DE)
- University Children's Hospital Tübingen(DE)
- Medical Solutions(GB)
- Max Planck Institute for Metabolism Research(DE)
- Max Planck Society(DE)
- Siemens (Germany)(DE)
- Siemens Healthcare (Germany)(DE)
- University of Tennessee System(US)
- University of Tennessee at Knoxville(US)
- University of Tennessee Medical Center(US)