Dies ist eine Übersichtsseite mit Metadaten zu dieser wissenschaftlichen Arbeit. Der vollständige Artikel ist beim Verlag verfügbar.
Molecular tracers for the PET and SPECT imaging of disease
364
Zitationen
2
Autoren
2010
Jahr
Abstract
The development of positron emission tomography (PET) and single photon emission computed tomography (SPECT) imaging continues to grow due to the ability of these techniques to allow the non-invasive in vivo visualisation of biological processes at the molecular and cellular levels. As well as finding application for the diagnosis of disease, these techniques have also been used in the drug discovery process. Crucial to the growth of these techniques is the continued development of molecular probes that can bind to the target biological receptor with high selectivity. This tutorial review describes the use of PET and SPECT for molecular imaging and highlights key strategies for the development of molecular probes for the imaging of both cancer and neurological diseases.
Ähnliche Arbeiten
Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures.
1981 · 14.246 Zit.
The nuclear receptor superfamily: The second decade
1995 · 6.967 Zit.
A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity
1984 · 5.023 Zit.
Screening λgt Recombinant Clones by Hybridization to Single Plaques in Situ
1977 · 4.664 Zit.
Abiraterone and Increased Survival in Metastatic Prostate Cancer
2011 · 4.376 Zit.