Construction of a Diagnostic Model for Lymph Node Metastasis of the Papillary Thyroid Carcinoma Using Preoperative Ultrasound Features and Imaging Omics

Abstract

In this paper, we mainly adopted 337 patients who had undergone the surgery on lymph node metastasis of papillary thyroid carcinoma (PTC) as the sample population. In order to provide clinical reference for the intelligent decision-making in treatment plan and improvement of prognosis, we utilized ultrasound features and imaging features to construct five early diagnosis models for patients based on the ultrasound features, imaging features, and combined features. The model integrated with broad learning system (BLS) showed the best performance, with the area under the curve (AUC) of 0.857 (95% confidence interval (CI): 0.811-0.902)) and the accuracy of 0.805 (95% CI: 0.759-0.850). For demographic and clinical features, the prediction effect was also good, with the AUC more than 0.700.

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