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A critical analysis of neuro-oncology clinical trials
22
Zitationen
4
Autoren
2023
Jahr
Abstract
Low randomization rates, underutilization of controls, and overestimation of effect size, particularly pronounced in early-phase trials, impede generalizability of results. Suboptimal designs may be driven by accrual challenges, underscoring the need for cooperative efforts and novel designs. The limited results reporting highlights the need to incentivize data reporting and harmonization.
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