DeepSeek-R1 vs OpenAI o1 for Ophthalmic Diagnoses and Management Plans

Abstract

DeepSeek-R1 outperformed OpenAI o1 in diagnosis and management across subspecialties while lowering operating costs, supporting the potential of open-weight, reinforcement learning-augmented LLMs as scalable and cost-saving tools for clinical decision support. Further investigations should evaluate safety guardrails and assess performance of self-hosted adaptations of DeepSeek-R1 with domain-specific ophthalmic expertise to optimize clinical utility.

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