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The Role of Big Data in Health and Biomedical Research
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2015
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Abstract
ABSTRACT Nearly every major scientific revolution in history has been driven by one thing: Data. Today, the availability of Big Data from a wide variety of sources is transforming health and biomedical research into what is increasingly an information science, where discovery is driven by our ability to effectively collect, manage, analyze, and interpret data. Much of this has been driven by an extraordinary drop in the economics of mapping a human genome (the entirety of DNA in each of our cells; Figure 1), where the cost has dropped from hundreds of millions of dollars to a few thousand dollars and the time to generate those data has fallen from many months to little more than a day. This has propelled DNA sequencing technologies from the research laboratory into the mainstream of medical practice and positioned “precision genomic medicine” to become standard of care in treating cancer and other diseases.
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