Design and Evaluation of EMPATHICA: A Chatbot for Enhancing Medication Literacy.

Abstract

Health literacy significantly impacts patient outcomes, yet many struggle to understand complex medication information. Medication non-adherence often results from poor comprehension of drug instructions and contributes to preventable hospitalizations and poor treatment outcomes. With the increasing use of digital health interventions, AI-powered chatbots present an opportunity to improve patient access to understandable and personalized medication information. This study evaluates the usability, accessibility, and effectiveness of EMPATHICA, an AI-powered chatbot designed to provide patient-centric medication information. The study assesses whether chatbot-generated responses improve patient comprehension and engagement. The research observed the interaction between participants and the web-based application, where participants asked the chatbot to measure the chatbot's usability and accuracy using various qualitative and quantitative measures and expert physician evaluation of the responses. AI-driven chatbots have the potential to bridge health literacy gaps by providing clear and accessible medication information. By evaluating EMPATHICA, this study contributes to the growing field of AI applications supporting patient-informed medication use.

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