How much Medical Knowledge do LLMs have? An Evaluation of Medical Knowledge Coverage for LLMs

Abstract

Previous evaluation frameworks for large language models (LLMs) have mostly relied on existing question-answering benchmarks, which are primarily task-oriented rather than knowledge-oriented.In the medical domain, however, the effective deployment of LLMs necessitates a thorough evaluation of their medical knowledge coverage.To this end, we propose a systematic evaluation framework, MedKGEval, to assess the coverage of medical knowledge in LLMs through the lens of medical knowledge graphs (KGs).MedKGEval transforms various levels of knowledge (entity-level, relation-level, and subgraph-level) from the medical KG into distinct groups of question-answer pairs, which serve as comprehensive evaluation benchmarks.In addition to traditional task-oriented evaluations, MedKGEval introduces a novel knowledge-oriented evaluation approach that encompasses the assessment of knowledge coverage across entities, relations, and triples.This multi-aspect evaluation approach allows for a more nuanced understanding of LLMs' knowledge coverage in the medical context.Using these benchmarks, we conduct a systematic evaluation of 11 LLMs from multiple perspectives, revealing insights into their strengths and weaknesses in medical knowledge memorization and reasoning.

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