Supporting documentation for Intervention approaches to address allostatic load-associated health disparities across high income and low/middle- income countries: A Scoping Review

Abstract

This scoping review examines the breadth of literature on intervention approaches targeting health disparities associated with allostatic load. The allostatic load framework provides a foundation for understanding the impact of chronic stress on health outcomes and disparities. While aspects of the framework have been well studied, targeted approaches to addressing health disparities remain under-explored.The review includes selected studies from both high-income countries (HICs) and low/middle-income countries (LMICs) to illustrate meaningful interventions in different settings. The uploaded materials include key articles referenced in the review, covering HIC and LMIC contexts, as well as works cited by the authors. Additionally, the query process deriving these materials are supported the PRISMA flow model. PRISMA-ScR Checklist and collated materials are referenced in table format.The findings highlight a substantial gap in research on interventions addressing allostatic load-associated health disparities. Future research should prioritize systematic analysis of intervention approaches and incorporate modern methodological approaches using artificial intelligence (AI) with particular attention to strategies that mitigate the global burden of disease and mortality attributable to allostatic load.

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